Members of MIT's LCP and Biology Department were instrumental in providing user requirements, test feedback and architectural considerations that were incorporated into the original design. Specifically Roger Mark, George Moody, Wei Zong, Thomas Heldt, Ali Saeed and Monty Krieger, all from MIT, provided an exceptional and knowledgeable core of insight and experience that helped propel development. Similarly in later stages of development Nic Chronos and Fernando Tondato, both of the American Cardiovascular Research Institute in Atlanta, provided exceptional user feedback and suggestions for further development of Hermes into a cardiovascular toxicity screening tool. Nic Chronos in particular devoted substantial time, effort, and financial resources toward building Hermes into a tool that could be considered the beginnings of a marketable product.

The development of Hermes as a commercial product would not have been possible without Doug Pierce, who applied his extensive experience in technology commercialization to help Oefinger Enterprises, Inc. to transition Hermes from academia into a licensed technology product. He has continued to provide substantial devotion of time, money and effort toward building business logic to complement and otherwise raw technology.